Category: Biology

. . . . . . . Í N D I C E . CONTENIDO  Pág. . AGRADECIMIENTO  ii DEDICATORIA  iii RESPONSABILIDAD  vi RESUMEN  vi SUMMARY  viii . CAPÍTULO I . %1.1.PLANTEAMIENTO DEL PROBLEMA  2 %1.2.JUSTIFICACIÓN  5 . CAPÍTULO II . %1.2.MARCO TEÓRICO  8 %1.%2.1.Herpes Viral Simplex – Generalidades  8 %1.%2.2.Etiología  9 %1.%2.3.Biología del Herpes Virus Simplex II  9 %1.%2.%3.1.Estructura del virón y eventos tempranos  9 %1.%2.%3.2.Infección primaria  10 %1.%2.%3.3.Expresión génica  11 %1.%2.4.Epidemiología  15 %1.%2.5.Factores de riesgo  16 %1.%2.6.Transmisión de herpes genital  17 %1.%2.7.Etapas de la infección por HVS 2  19 %1.%2.8.Inmunidad humoral frente a la infección  19 %1.%2.9.Infección materna  21 %1.%2.10.Diagnóstico del herpes genital  22 %1.%2.11.Profilaxis…….  25 . CAPÍTULO III . %1.1.OBJETIVOS  27 %1.%2.1.Objetivo General  27 %1.%2.2.Objetivos Específicos  27 %1.2.DISEÑO METODOLÓGICO  28 %1.%2.3.Tipo de Estudio  28 %1.%2.4.Universo y Muestra  28 %1.%2.5.Criterios de Inclusión  29 %1.%2.6.Criterios de Exclusión  30 %1.%2.7.Operacionalización de Variables  30 %1.%2.8.Plan de Observación de campo  31 %1.%2.9.Procedimientos  31 . CAPÍTULO IV . 4.1. RESULTADOS Y ANÁLISIS DE LA INFORMACIÓN  37 . CAPÍTULO V . 5.1. DISCUSIÓN  59 . CAPÍTULO VI . %1.1.CONCLUSIONES  62 %1.2.RECOMENDACIONES  63 . REFERENCIAS BIBLIOGRÁFICAS  64 BIBLIOGRAFÍA  66 ANEXOS  69...

The connective tissue is edematous and densely infiltrated with plasma cells (approximately 80%) and lymphocytes and a scattering of PMNs. The blood vessels are increased in number, dilated, and engorged. The connective tissue exhibits varying degrees of degeneration. Single or multiple necrotic foci are occasionally present. In addition to exudative and degenerative changes, the connective tissue shows proliferation of the endothelial cells, with newly formed capillaries, fibroblasts, and collagen fibers. The junctional epithelium at the base of the pocket is usually much shorter than that of a normal sulcus. Although marked variations are found as to length, width, and condition of the epithelial cells, usually the coronoapical length of the junctional epithelium is reduced to only 50 to 100 mm. The cells may be well formed and in good condition or may exhibit slight to marked degeneration. The most severe degenerative changes in the periodontal pocket occur along the lateral wall. The epithelium of the lateral wall of the pocket presents striking proliferative and degenerative changes. Epithelial buds or interlacing cords of epithelial cells project from the lateral wall into the adjacent inflamed connective tissue and frequently extend farther apically than the junctional epithelium. These epithelial projections, as well as the remainder of the lateral epithelium, are densely infiltrated by leukocytes and edema from the inflamed connective tissue. The cells undergo vacuolar degeneration and rupture to form vesicles. Progressive degeneration and necrosis of the epithelium lead to ulceration of the lateral wall, exposure of the underlying – markedly inflamed connective tissue, and suppuration. In some cases acute inflammation is superimposed on the underlying chronic changes. The severity of the degenerative changes is not necessarily related to pocket depth. Ulceration of the lateral wall may occur in shallow pockets, and deep pockets are occasionally observed in which the lateral epithelium is relatively intact and shows only slight degeneration. The epithelium at the gingival crest of a periodontal pocket is generally intact and thickened, with prominent rete pegs. Bacterial Invasion: Bacterial invasion of the apical and lateral areas of the pocket wall may occur in human chronic periodontitis. Filaments, rods, and coccoid organisms with predominant gram-negative cell walls have been found in intercellular spaces of the epithelium. Bacteria invade the intercellular space initially under exfoliating epithelial cells, but they are also found between deeper epithelial cells and accumulating onthe basement lamina. Some bacteria traverse the basement lamina and invade the subepithelial connective...